Phenotypic and metabolic features of mouse diaphragm and gastrocnemius muscles in chronic lung carcinogenesis: influence of underlying emphysema

BACKGROUND: Muscle wasting negatively impacts the progress of chronic diseases such as lung cancer (LC) and emphysema, which are in turn interrelated. OBJECTIVES: We hypothesized that muscle atrophy and body weight loss may develop in an experimental mouse model of lung carcinogenesis, that the prof...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Salazar-Degracia, Anna, Blanco, David, Vilà-Ubach, Mònica, de Biurrun, Gabriel, de Solórzano, Carlos Ortiz, Montuenga, Luis M., Barreiro, Esther
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994253/
https://ncbi.nlm.nih.gov/pubmed/27549759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1003-9
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