Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1

BACKGROUND: Keloids are an extreme form of abnormal scarring that result from a pathological fibroproliferative wound healing process. The molecular mechanisms driving keloid pathology remain incompletely understood, hindering development of targeted, effective therapies. Recent studies in our labor...

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Publicat a:Burns Trauma
Autors principals: Hahn, Jennifer M., McFarland, Kevin L., Combs, Kelly A., Supp, Dorothy M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994224/
https://ncbi.nlm.nih.gov/pubmed/27574697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41038-016-0055-7
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