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Characterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome

Recent evidence has shown that the sperm epigenome is vulnerable to dynamic modifications arising from a variety of paternal environment exposures and that this legacy can serve as an important determinant of intergenerational inheritance. It has been postulated that such exchange is communicated to...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Reilly, Jackson N., McLaughlin, Eileen A., Stanger, Simone J., Anderson, Amanda L., Hutcheon, Kate, Church, Kiralee, Mihalas, Bettina P., Tyagi, Sonika, Holt, Janet E., Eamens, Andrew L., Nixon, Brett
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994100/
https://ncbi.nlm.nih.gov/pubmed/27549865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31794
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