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Human monoclonal islet cell antibodies from a patient with insulin-dependent diabetes mellitus reveal glutamate decarboxylase as the target antigen.

The autoimmune phenomena associated with destruction of the beta cell in pancreatic islets and development of type 1 (insulin-dependent) diabetes mellitus (IDDM) include circulating islet cell antibodies. We have immortalized peripheral blood lymphocytes from prediabetic individuals and patients wit...

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Detalhes bibliográficos
Main Authors: Richter, W, Endl, J, Eiermann, T H, Brandt, M, Kientsch-Engel, R, Thivolet, C, Jungfer, H, Scherbaum, W A
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49941/
https://ncbi.nlm.nih.gov/pubmed/1382289
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