Disease-Homologous Mutation in the Cation Diffusion Facilitator Protein MamM Causes Single-Domain Structural Loss and Signifies Its Importance

Cation diffusion facilitators (CDF) are highly conserved, metal ion efflux transporters that maintain divalent transition metal cation homeostasis. Most CDF proteins contain two domains, the cation transporting transmembrane domain and the regulatory cytoplasmic C-terminal domain (CTD). MamM is a ma...

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Publicado no:Sci Rep
Main Authors: Barber-Zucker, Shiran, Uebe, René, Davidov, Geula, Navon, Yotam, Sherf, Dror, Chill, Jordan H., Kass, Itamar, Bitton, Ronit, Schüler, Dirk, Zarivach, Raz
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994047/
https://ncbi.nlm.nih.gov/pubmed/27550551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31933
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