Disease-Homologous Mutation in the Cation Diffusion Facilitator Protein MamM Causes Single-Domain Structural Loss and Signifies Its Importance

Cation diffusion facilitators (CDF) are highly conserved, metal ion efflux transporters that maintain divalent transition metal cation homeostasis. Most CDF proteins contain two domains, the cation transporting transmembrane domain and the regulatory cytoplasmic C-terminal domain (CTD). MamM is a ma...

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Publicado en:Sci Rep
Autores principales: Barber-Zucker, Shiran, Uebe, René, Davidov, Geula, Navon, Yotam, Sherf, Dror, Chill, Jordan H., Kass, Itamar, Bitton, Ronit, Schüler, Dirk, Zarivach, Raz
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994047/
https://ncbi.nlm.nih.gov/pubmed/27550551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31933
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