MiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia

Previous results indicated that miR-146b-5p is downregulated by TAL1, a transcription factor critical for early hematopoiesis that is frequently overexpressed in T-cell acute lymphoblastic leukemia (T-ALL) where it has an oncogenic role. Here, we confirmed that miR-146b-5p expression is lower in TAL...

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Vydáno v:Sci Rep
Hlavní autoři: Correia, Nádia C., Fragoso, Rita, Carvalho, Tânia, Enguita, Francisco J., Barata, João T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994040/
https://ncbi.nlm.nih.gov/pubmed/27550837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31894
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