TGF-β/BAMBI pathway dysfunction contributes to peripheral Th17/Treg imbalance in chronic obstructive pulmonary disease

BMP and activin membrane-bound inhibitor (BAMBI) is postulated to inhibit or modulate transforming growth factor β (TGF-β) signaling. Furthermore, strong upregulation of BAMBI expression following in vitro infection of chronic obstructive pulmonary disease (COPD) lung tissue has been demonstrated. I...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zhang, Jian-Chu, Chen, Gang, Chen, Long, Meng, Zhao-Ji, Xiong, Xian-Zhi, Liu, Hong-Ju, Jin, Yang, Tao, Xiao-Nan, Wu, Jiang-Hua, Sun, Sheng-Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994021/
https://ncbi.nlm.nih.gov/pubmed/27549738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31911
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