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The Biological Effects of IL-21 Signaling on B-Cell-Mediated Responses in Organ Transplantation

Antibody-mediated rejection has emerged as one of the major issues limiting the success of organ transplantation. It exerts a highly negative impact on graft function and outcome, and effective treatment is lacking. The triggers for antibody development, and the mechanisms leading to graft dysfuncti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Wu, Yongkang, van Besouw, Nicole M., Shi, Yunying, Hoogduijn, Martin J., Wang, Lanlan, Baan, Carla C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4994014/
https://ncbi.nlm.nih.gov/pubmed/27602031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00319
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