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Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae

The import of basic amino acids in Saccharomyces cerevisiae has been reported to be unidirectional, which is not typical of how secondary transporters work. Since studies of energy coupling and transport kinetics are complicated in vivo, we purified the major lysine transporter (Lyp1) of yeast and r...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Bianchi, Frans, Klooster, Joury S. van ‘t, Ruiz, Stephanie J., Luck, Katja, Pols, Tjeerd, Urbatsch, Ina L., Poolman, Bert
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993999/
https://ncbi.nlm.nih.gov/pubmed/27550794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31443
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