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Genome-Wide Transcriptional Analysis Reveals the Protection against Hypoxia-Induced Oxidative Injury in the Intestine of Tibetans via the Inhibition of GRB2/EGFR/PTPN11 Pathways

The molecular mechanisms for hypoxic environment causing the injury of intestinal mucosal barrier (IMB) are widely unknown. To address the issue, Han Chinese from 100 m altitude and Tibetans from high altitude (more than 3650 m) were recruited. Histological and transcriptome analyses were performed....

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Li, Kang, Gesang, Luobu, Dan, Zeng, Gusang, Lamu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993941/
https://ncbi.nlm.nih.gov/pubmed/27594973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6967396
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