Overview of recurrent chromosomal losses in retinoblastoma detected by low coverage next generation sequencing

Genes are frequently lost or gained in malignant tumors and the analysis of these changes can be informative about the underlying tumor biology. Retinoblastoma is a pediatric intraocular malignancy, and since deletions in chromosome 13 have been described in this tumor, we performed genome wide sequ...

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Publié dans:Cancer Genet
Auteurs principaux: García-Chequer, A.J., Méndez-Tenorio, A., Olguín-Ruiz, G., Sánchez-Vallejo, C., Isa, P., Arias, C.F., Torres, J., Hernández-Angeles, A., Ramírez-Ortiz, M.A., Lara, C., Cabrera-Muñoz, M.L., Sadowinski-Pine, S., Bravo-Ortiz, J.C., Ramón-García, G., Diegopérez-Ramírez, J., Ramírez-Reyes, G., Casarrubias-Islas, R., Ramírez, J., Orjuela, M.A., Ponce-Castañeda, M.V.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993565/
https://ncbi.nlm.nih.gov/pubmed/26883451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2015.12.001
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