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Correlating Calmodulin Landscapes with Chemical Catalysis in Neuronal Nitric Oxide Synthase using Time-Resolved FRET and a 5-Deazaflavin Thermodynamic Trap

[Image: see text] A major challenge in enzymology is the need to correlate the dynamic properties of enzymes with, and understand the impact on, their catalytic cycles. This is especially the case with large, multicenter enzymes such as the nitric oxide synthases (NOSs), where the importance of dyna...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Hedison, Tobias M., Leferink, Nicole G. H., Hay, Sam, Scrutton, Nigel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993522/
https://ncbi.nlm.nih.gov/pubmed/27563493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.6b01280
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