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Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity

Deoxyxylulose 5-phosphate synthase (DXS), a thiamine diphosphate (ThDP) dependent enzyme, plays a regulatory role in the methylerythritol 4-phosphate (MEP) pathway. Isopentenyl diphosphate (IDP) and dimethylallyl diphosphate (DMADP), the end products of this pathway, inhibit DXS by competing with Th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Banerjee, Aparajita, Preiser, Alyssa L., Sharkey, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993486/
https://ncbi.nlm.nih.gov/pubmed/27548482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161534
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