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Impaired cell proliferation in regenerating liver of 3 β-hydroxysterol Δ14-reductase (TM7SF2) knock-out mice

The liver is the most important organ in cholesterol metabolism, which is instrumental in regulating cell proliferation and differentiation. The gene Tm7sf2 codifies for 3 β-hydroxysterol-Δ(14)-reductase (C14-SR), an endoplasmic reticulum resident protein catalyzing the reduction of C14-unsaturated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Bartoli, Daniela, Piobbico, Danilo, Bellet, Marina Maria, Bennati, Anna Maria, Roberti, Rita, Della Fazia, Maria Agnese, Servillo, Giuseppe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993425/
https://ncbi.nlm.nih.gov/pubmed/27341299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1195939
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