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HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice

The heteromeric receptor complex between 5-HT(2A) and mGlu2 has been implicated in some of the behavioral phenotypes in mouse models of psychosis(1,2). Consequently, investigation of structural details of the interaction between 5-HT(2A) and mGlu2 affecting schizophrenia-related behaviors represents...

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Publicado en:J Vis Exp
Autores principales: Holloway, Terrell, Moreno, Jose L., González-Maeso, Javier
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993366/
https://ncbi.nlm.nih.gov/pubmed/27501227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53717
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