INHALED ALPHA(1)-PROTEINASE INHIBITOR THERAPY IN PATIENTS WITH CYSTIC FIBROSIS

BACKGROUND: Inhaled alpha(1)-proteinase inhibitor (PI) is known to reduce neutrophil elastase burden in some patients with CF. This phase 2a study was designed to test inhaled Alpha-1 HC, a new aerosolized alpha(1)-PI formulation, in CF patients. METHODS: We performed a randomized, double-blind, pla...

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Detalhes bibliográficos
Publicado no:J Cyst Fibros
Main Authors: Gaggar, Amit, Chen, Junliang, Chmiel, James F, Dorkin, Henry L, Flume, Patrick A, Griffin, Rhonda, Nichols, David, Donaldson, Scott H
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993024/
https://ncbi.nlm.nih.gov/pubmed/26321218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2015.07.009
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