IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice

Serum level of IL-21 is increased in patients with inflammatory bowel diseases (IBD), suggesting that IL-21/IL-21 receptor (IL-21R) signaling may be involved in the pathogenesis of IBD. However, the role of IL-21/IL-21 receptor signaling plays in the pathogenesis of IBD is not very clear. In this st...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Yuanyuan, Jiang, Xuefeng, Zhu, Junfeng, Dan Yue, Zhang, Xiaoqing, Wang, Xiao, You, Yong, Wang, Biao, Xu, Ying, Lu, Changlong, Sun, Xun, Yoshikai, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992961/
https://ncbi.nlm.nih.gov/pubmed/27545302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31881
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