Dynamics of Human Mitochondrial Complex I Assembly: Implications for Neurodegenerative Diseases

Neurons are extremely energy demanding cells and highly dependent on the mitochondrial oxidative phosphorylation (OXPHOS) system. Mitochondria generate the energetic potential via the respiratory complexes I to IV, which constitute the electron transport chain (ETC), together with complex V. These r...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Giachin, Gabriele, Bouverot, Romain, Acajjaoui, Samira, Pantalone, Serena, Soler-López, Montserrat
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992684/
https://ncbi.nlm.nih.gov/pubmed/27597947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00043
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