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Cutaneous tissue damage induces long-lasting nociceptive sensitization and regulation of cellular stress- and nerve injury-associated genes in sensory neurons
Tissue damage is one of the major etiological factors in the emergence of chronic/persistent pain, although mechanisms remain enigmatic. Using incision of the back skin of adult rats as a model for tissue damage, we observed sensitization in a nociceptive reflex enduring to 28 days post-incision (DP...
Tallennettuna:
Julkaisussa: | Exp Neurol |
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Päätekijät: | , , , , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2016
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992590/ https://ncbi.nlm.nih.gov/pubmed/27264359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.06.002 |
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