Nocturnal Hypoxia Induced Oxidative Stress Promotes Progression of Pediatric Non-Alcoholic Fatty Liver Disease

BACKGROUND: Oxidative stress is proposed as a central mediator in NAFLD pathogenesis, but the specific trigger for reactive oxygen species generation has not been clearly delineated. In addition, emerging evidence shows that obesity-related obstructive sleep apnea (OSA) and nocturnal hypoxia are ass...

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Publicado en:J Hepatol
Autores principales: Sundaram, Shikha S., Halbower, Ann, Pan, Zhaoxing, Robbins, Kristen, Capocelli, Kelley E., Klawitter, Jelena, Shearn, Colin T., Sokol, Ronald J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992457/
https://ncbi.nlm.nih.gov/pubmed/27501738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2016.04.010
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