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Inverting the Topology of a Transmembrane Protein by Regulating the Translocation of the First Transmembrane Helix
TM4SF20 (transmembrane 4 L6 family 20) is a polytopic membrane protein that inhibits proteolytic processing of CREB3L1 (cAMP response element-binding protein 3-like 1), a membrane-bound transcription factor that blocks cell division and activates collagen synthesis. Here we report that ceramide stim...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4992448/ https://ncbi.nlm.nih.gov/pubmed/27499293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.06.032 |
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