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Iron Overload or Oxidative Stress? Insight into a Mechanism of Early Cardiac Manifestations of Asymptomatic Hereditary Hemochromatosis Subjects with C282Y Homozygosity

Hereditary hemochromatosis (HH) is a genetic disorder which affects the heart due to systemic iron overload and concomitant elevated oxidative stress. Increasing numbers of patients are diagnosed at an asymptomatic stage due to genetic testing. Subclinical abnormal left ventricular diastolic functio...

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Détails bibliographiques
Publié dans:J Cardiovasc Transl Res
Auteurs principaux: Shizukuda, Yukitaka, Tripodi, Dorothy J., Rosing, Douglas R.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992414/
https://ncbi.nlm.nih.gov/pubmed/27271161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-016-9704-2
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