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Iron Overload or Oxidative Stress? Insight into a Mechanism of Early Cardiac Manifestations of Asymptomatic Hereditary Hemochromatosis Subjects with C282Y Homozygosity

Hereditary hemochromatosis (HH) is a genetic disorder which affects the heart due to systemic iron overload and concomitant elevated oxidative stress. Increasing numbers of patients are diagnosed at an asymptomatic stage due to genetic testing. Subclinical abnormal left ventricular diastolic functio...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Transl Res
Main Authors: Shizukuda, Yukitaka, Tripodi, Dorothy J., Rosing, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992414/
https://ncbi.nlm.nih.gov/pubmed/27271161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-016-9704-2
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