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Mutations in gonadotropin-releasing hormone signaling pathway in two nIHH patients with successful pregnancy outcomes

BACKGROUND: Anomalous levels of gonadotropin-releasing hormone (GnRH) secretion result in a variety of reproductive phenotypes associated with infertility or subfertility. The normosmic isolated hypogonadotropic hypogonadism (nIHH) is due to a failure of either GnRH pulsatile secretion in hypothalam...

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Detalles Bibliográficos
Publicado en:Reprod Biol Endocrinol
Main Authors: Zernov, Nikolay, Skoblov, Mikhail, Baranova, Ancha, Boyarsky, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992333/
https://ncbi.nlm.nih.gov/pubmed/27544332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-016-0183-8
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