Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia

In acute myeloid leukaemia (AML) initiating pre-leukaemic lesions can be identified through three major hallmarks: their early occurrence in the clone, their persistence at relapse and their ability to initiate multilineage haematopoietic repopulation and leukaemia in vivo. Here we analyse the clona...

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Publicado no:Nat Commun
Main Authors: Hirsch, Pierre, Zhang, Yanyan, Tang, Ruoping, Joulin, Virginie, Boutroux, Hélène, Pronier, Elodie, Moatti, Hannah, Flandrin, Pascale, Marzac, Christophe, Bories, Dominique, Fava, Fanny, Mokrani, Hayat, Betems, Aline, Lorre, Florence, Favier, Rémi, Féger, Frédéric, Mohty, Mohamad, Douay, Luc, Legrand, Ollivier, Bilhou-Nabera, Chrystèle, Louache, Fawzia, Delhommeau, François
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992157/
https://ncbi.nlm.nih.gov/pubmed/27534895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12475
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