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Spatial organization of chromatin domains and compartments in single chromosomes

The spatial organization of chromatin critically impacts genome function. Recent chromosome-conformation-capture studies have revealed topologically-associating domains (TADs) as a conserved feature of chromatin organization, but how TADs are spatially organized in individual chromosomes remains unk...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Wang, Siyuan, Su, Jun-Han, Beliveau, Brian J., Bintu, Bogdan, Moffitt, Jeffrey R., Wu, Chao-ting, Zhuang, Xiaowei
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991974/
https://ncbi.nlm.nih.gov/pubmed/27445307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf8084
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