Structural analysis of a signal peptide inside the ribosome tunnel by DNP MAS NMR

Proteins are synthesized in cells by ribosomes and, in parallel, prepared for folding or targeting. While ribosomal protein synthesis is progressing, the nascent chain exposes amino-terminal signal sequences or transmembrane domains that mediate interactions with specific interaction partners, such...

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Vydáno v:Sci Adv
Hlavní autoři: Lange, Sascha, Franks, W. Trent, Rajagopalan, Nandhakishore, Döring, Kristina, Geiger, Michel A., Linden, Arne, van Rossum, Barth-Jan, Kramer, Günter, Bukau, Bernd, Oschkinat, Hartmut
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991931/
https://ncbi.nlm.nih.gov/pubmed/27551685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1600379
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