Comparative Decellularization and Recellularization of Wild-Type and Alpha 1,3 Galactosyltransferase Knockout Pig Lungs: A Model for Ex Vivo Xenogeneic Lung Bioengineering and Transplantation

Background: A novel potential approach for lung transplantation could be to utilize xenogeneic decellularized pig lung scaffolds that are recellularized with human lung cells. However, pig tissues express several immunogenic proteins, notably galactosylated cell surface glycoproteins resulting from...

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Udgivet i:Tissue Eng Part C Methods
Main Authors: Platz, Joseph, Bonenfant, Nicholas R., Uhl, Franziska E., Coffey, Amy L., McKnight, Tristan, Parsons, Charles, Sokocevic, Dino, Borg, Zachary D., Lam, Ying-Wai, Deng, Bin, Fields, Julia G., DeSarno, Michael, Loi, Roberto, Hoffman, Andrew M., Bianchi, John, Dacken, Brian, Petersen, Thomas, Wagner, Darcy E., Weiss, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991572/
https://ncbi.nlm.nih.gov/pubmed/27310581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2016.0109
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