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Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma

In glioma, microglia and macrophages are the largest population of tumor-infiltrating cells, referred to as glioma associated macrophages (GAMs). Herein, we sought to determine the role of Suppressor of Cytokine Signaling 3 (SOCS3), a negative regulator of Signal Transducer and Activator of Transcri...

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Publicat a:Oncotarget
Autors principals: McFarland, Braden C., Marks, Margaret P., Rowse, Amber L., Fehling, Samuel C., Gerigk, Magda, Qin, Hongwei, Benveniste, Etty N.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991480/
https://ncbi.nlm.nih.gov/pubmed/26967393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7992
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