Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells

Porcine circovirus type 2 (PCV2) is the primary cause of porcine circovirus disease, and ochratoxin A (OTA)-induced oxidative stress promotes PCV2 replication. In humans, selenoprotein S (SelS) has antioxidant ability, but it is unclear whether SelS affects viral infection. Here, we stably transfect...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gan, Fang, Hu, Zhihua, Huang, Yu, Xue, Hongxia, Huang, Da, Qian, Gang, Hu, Junfa, Chen, Xingxiang, Wang, Tian, Huang, Kehe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991468/
https://ncbi.nlm.nih.gov/pubmed/26943035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7814
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