A BRCA1 deficient, NFκB driven immune signal predicts good outcome in triple negative breast cancer

Triple negative (TNBCs) and the closely related Basal-like (BLBCs) breast cancers are a loosely defined collection of cancers with poor clinical outcomes. Both show strong similarities with BRCA1-mutant breast cancers and BRCA1 dysfunction, or ‘BRCAness’, is observed in a large proportion of sporadi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Buckley, Niamh E., Haddock, Paula, De Matos Simoes, Ricardo, Parkes, Eileen, Irwin, Gareth, Emmert-Streib, Frank, McQuaid, Stephen, Kennedy, Richard, Mullan, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991425/
https://ncbi.nlm.nih.gov/pubmed/26943587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7865
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