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Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

Production of human mesenchymal stem cells for allogeneic cell therapies requires scalable, cost‐effective manufacturing processes. Microcarriers enable the culture of anchorage‐dependent cells in stirred‐tank bioreactors. However, no robust, transferable methodology for microcarrier selection exist...

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Detaylı Bibliyografya
Yayımlandı:Biotechnol J
Asıl Yazarlar: Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Hewitt, Christopher J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: WILEY‐VCH Verlag 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991290/
https://ncbi.nlm.nih.gov/pubmed/26632496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201400862
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