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Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

Production of human mesenchymal stem cells for allogeneic cell therapies requires scalable, cost‐effective manufacturing processes. Microcarriers enable the culture of anchorage‐dependent cells in stirred‐tank bioreactors. However, no robust, transferable methodology for microcarrier selection exist...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biotechnol J
Prif Awduron: Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Hewitt, Christopher J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: WILEY‐VCH Verlag 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991290/
https://ncbi.nlm.nih.gov/pubmed/26632496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201400862
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