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Systematic microcarrier screening and agitated culture conditions improves human mesenchymal stem cell yield in bioreactors

Production of human mesenchymal stem cells for allogeneic cell therapies requires scalable, cost‐effective manufacturing processes. Microcarriers enable the culture of anchorage‐dependent cells in stirred‐tank bioreactors. However, no robust, transferable methodology for microcarrier selection exist...

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Detalhes bibliográficos
Publicado no:Biotechnol J
Main Authors: Rafiq, Qasim A., Coopman, Karen, Nienow, Alvin W., Hewitt, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991290/
https://ncbi.nlm.nih.gov/pubmed/26632496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201400862
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