Induction of tolerance to an IgG autoantibody.

Nonautoimmune mice transgenic for the heavy chain of an IgG2b anti-double-stranded-DNA antibody express the transgene in lymphoid organs and display partial allelic exclusion of this gamma 2b transgene. The spleens of these mice are characterized by marked B-cell depletion. Although there are B cell...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Offen, D, Spatz, L, Escowitz, H, Factor, S, Diamond, B
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC49912/
https://ncbi.nlm.nih.gov/pubmed/1518867
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