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Solid-state NMR characterization of amphomycin effects on peptidoglycan and wall teichoic acid biosyntheses in Staphylococcus aureus

Amphomycin and MX-2401 are cyclic lipopeptides exhibiting bactericidal activities against Gram-positive pathogens. Amphomycin and MX-2401 share structural similarities with daptomycin, but unlike daptomycin they do not target bacterial membrane. In this study, we investigate in vivo modes of action...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Singh, Manmilan, Chang, James, Coffman, Lauryn, Kim, Sung Joon
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990924/
https://ncbi.nlm.nih.gov/pubmed/27538449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31757
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