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Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons

Synapse formation and plasticity depend on nuclear transcription and site-specific protein targeting, but the molecular mechanisms that coordinate these steps have not been well defined. The MEN1 tumor suppressor gene, which encodes the protein menin, is known to induce synapse formation and plastic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Getz, Angela M., Visser, Frank, Bell, Erin M., Xu, Fenglian, Flynn, Nichole M., Zaidi, Wali, Syed, Naweed I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990912/
https://ncbi.nlm.nih.gov/pubmed/27538741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31779
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