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Generation of a novel transgenic rat model for tracing extracellular vesicles in body fluids

Extracellular vesicles (EVs) play an important role in the transfer of biomolecules between cells. To elucidate the intercellular transfer fate of EVs in vivo, we generated a new transgenic (Tg) rat model using green fluorescent protein (GFP)-tagged human CD63. CD63 protein is highly enriched on EV...

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Vydáno v:Sci Rep
Hlavní autoři: Yoshimura, Aya, Kawamata, Masaki, Yoshioka, Yusuke, Katsuda, Takeshi, Kikuchi, Hisae, Nagai, Yoshitaka, Adachi, Naoki, Numakawa, Tadahiro, Kunugi, Hiroshi, Ochiya, Takahiro, Tamai, Yoshitaka
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990884/
https://ncbi.nlm.nih.gov/pubmed/27539050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31172
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