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Function of high-mobility group A proteins in the DNA damage signaling for the induction of apoptosis
O(6)-Methylguanine produced in DNA can pair with thymine during DNA replication, thus leading to a G-to-A transition mutation. To prevent such outcomes, cells harboring O(6)-methylguanine-containing mispair undergo apoptosis that requires the function of mismatch repair (MMR) protein complex. To ide...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990841/ https://ncbi.nlm.nih.gov/pubmed/27538817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31714 |
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