Tetrapeptide inhibitors of protein farnesyltransferase: amino-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation.

Protein farnesyltransferase from rat brain transfers farnesyl residues to cysteine residues in tetrapeptides that conform to the sequence CA1A2X, where C is cysteine, A1 and A2 are aliphatic amino acids, and X is methionine or serine. When the A2 residue is aromatic [e.g., phenylalanine as in Cys-Va...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Brown, M S, Goldstein, J L, Paris, K J, Burnier, J P, Marsters, J C
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC49908/
https://ncbi.nlm.nih.gov/pubmed/1518863
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki