Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs

The main pathogenesis of intervertebral disc (IVD) herniation involves disruption of the annulus fibrosus (AF) caused by ageing or excessive mechanical stress and the resulting prolapse of the nucleus pulposus. Owing to the avascular nature of the IVD and lack of understanding the mechanisms that ma...

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Udgivet i:Nat Commun
Main Authors: Nakamichi, Ryo, Ito, Yoshiaki, Inui, Masafumi, Onizuka, Naoko, Kayama, Tomohiro, Kataoka, Kensuke, Suzuki, Hidetsugu, Mori, Masaki, Inagawa, Masayo, Ichinose, Shizuko, Lotz, Martin K., Sakai, Daisuke, Masuda, Koichi, Ozaki, Toshifumi, Asahara, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990710/
https://ncbi.nlm.nih.gov/pubmed/27527664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12503
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