miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells

Oxaliplatin resistance in colorectal cancers (CRC) is a major medical problem, and predictive markers are urgently needed. Recently, miR-625-3p was reported as a promising predictive marker. Herein, we show that miR-625-3p functionally induces oxaliplatin resistance in CRC cells, and identify the si...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rasmussen, Mads Heilskov, Lyskjær, Iben, Jersie-Christensen, Rosa Rakownikow, Tarpgaard, Line Schmidt, Primdal-Bengtson, Bjarke, Nielsen, Morten Muhlig, Pedersen, Jakob Skou, Hansen, Tine Plato, Hansen, Flemming, Olsen, Jesper Velgaard, Pfeiffer, Per, Ørntoft, Torben Falck, Andersen, Claus Lindbjerg
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990699/
https://ncbi.nlm.nih.gov/pubmed/27526785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12436
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