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Modeling the Pro-inflammatory Tumor Microenvironment in Acute Lymphoblastic Leukemia Predicts a Breakdown of Hematopoietic-Mesenchymal Communication Networks

Lineage fate decisions of hematopoietic cells depend on intrinsic factors and extrinsic signals provided by the bone marrow microenvironment, where they reside. Abnormalities in composition and function of hematopoietic niches have been proposed as key contributors of acute lymphoblastic leukemia (A...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Enciso, Jennifer, Mayani, Hector, Mendoza, Luis, Pelayo, Rosana
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990565/
https://ncbi.nlm.nih.gov/pubmed/27594840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00349
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