Neonatal Growth Restriction-Related Leptin Deficiency Enhances Leptin-Triggered Sympathetic Activation and Central Angiotensin II Receptor-Dependent Stress-Evoked Hypertension

BACKGROUND: Neonatal growth restriction (nGR) leads to leptin deficiency and increases the risk of hypertension. Previous studies have shown nGR-related hypertension is normalized by neonatal leptin (nLep) and exacerbated by psychological stress. With recent studies linking leptin and angiotensin si...

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Bibliografske podrobnosti
izdano v:Pediatr Res
Main Authors: Peotta, Veronica, Rahmouni, Kamal, Segar, Jeffrey L., Morgan, Donald A., Pitz, Kate M., Rice, Olivia M., Roghair, Robert D.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990468/
https://ncbi.nlm.nih.gov/pubmed/27049292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.64
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