X-ray Absorption Spectroscopic Characterization of the Diferric-peroxo Intermediate of Human Deoxyhypusine Hydroxylase in the Presence of its Substrate eIF5a

Human deoxyhypusine hydroxylase (hDOHH) is an enzyme that is involved in the critical post-translational modification of the eukaryotic translation initiation factor 5A (eIF5A). Following the conversion of a lysine residue on eIF5A to deoxyhypusine (Dhp) by deoxyhypusine synthase, hDOHH hydroxylates...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: Jasniewski, Andrew J., Engstrom, Lisa M., Vu, Van V., Park, Myung Hee, Que, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990465/
https://ncbi.nlm.nih.gov/pubmed/27380180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-016-1373-8
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