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Molecular dynamics-based refinement and validation for sub-5 Å cryo-electron microscopy maps
Two structure determination methods, based on the molecular dynamics flexible fitting (MDFF) paradigm, are presented that resolve sub-5 Å cryo-electron microscopy (EM) maps with either single structures or ensembles of such structures. The methods, denoted cascade MDFF and resolution exchange MDFF,...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4990421/ https://ncbi.nlm.nih.gov/pubmed/27383269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16105 |
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