Enhanced tumor delivery and antitumor response of doxorubicin-loaded albumin nanoparticles formulated based on a Schiff base

A novel method was developed here to prepare albumin-based nanoparticles (NPs) for improving the therapeutic and safety profiles of chemotherapeutic agents. This approach involved crosslinking bovine serum albumin (BSA) using a Schiff base-containing vanillin, into NPs and loading doxorubicin (DOX)...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Li, Fang, Zheng, Chunli, Xin, Junbo, Chen, Fangcheng, Ling, Hua, Sun, Linlin, Webster, Thomas J, Ming, Xin, Liu, Jianping
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990380/
https://ncbi.nlm.nih.gov/pubmed/27574421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S108689
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