Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in breast cancer patients treated with paclitaxel and docetaxel

BACKGROUND: Interindividual variability of pharmacogenetics may account for unpredictable neurotoxicities of taxanes. METHODS: From March 2011 to June 2015, female patients with operable breast cancer who had received docetaxel- or paclitaxel-containing adjuvant chemotherapy were included in this st...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Onco Targets Ther
Asıl Yazarlar: Kus, Tulay, Aktas, Gokmen, Kalender, Mehmet Emin, Demiryurek, Abdullah Tuncay, Ulasli, Mustafa, Oztuzcu, Serdar, Sevinc, Alper, Kul, Seval, Camci, Celaletdin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2016
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990373/
https://ncbi.nlm.nih.gov/pubmed/27574448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S106574
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