Towards Real-time Metabolic Profiling of Cancer with Hyperpolarized Succinate

PURPOSE: The energy-yielding mitochondrial Krebs cycle has been shown in many cancers and other diseases to be inhibited or mutated. In most cells, the Krebs cycle with oxidative phosphorylation generates approximately 90% of the adenosine triphosphate in the cell. We designed and hyperpolarized car...

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Опубликовано в: :J Mol Imaging Dyn
Главные авторы: Zacharias, Niki M., McCullough, Christopher R., Wagner, Shawn, Sailasuta, Napapon, Chan, Henry R., Lee, Youngbok, Hu, Jingzhe, Perman, William H., Henneberg, Cameron, Ross, Brian D., Bhattacharya, Pratip
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989923/
https://ncbi.nlm.nih.gov/pubmed/27547490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9937.1000123
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