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Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice

BACKGROUND: Multifunctional transcription factor (TF) gene EWS/EWSR1 is involved in various cellular processes such as transcription regulation, noncoding RNA regulation, splicing regulation, genotoxic stress response, and cancer generation. Role of a TF gene can be effectively studied by measuring...

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Bibliographic Details
Published in:BMC Med Genomics
Main Authors: Lee, Chai-Jin, Ahn, Hongryul, Lee, Sean Bong, Shin, Jong-Yeon, Park, Woong-Yang, Kim, Jong-Il, Lee, Junghee, Ryu, Hoon, Kim, Sun
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989891/
https://ncbi.nlm.nih.gov/pubmed/27534535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0195-4
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