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Evolution in spatially mixed host environments increases divergence for evolved fitness and intrapopulation genetic diversity in RNA viruses

Virus populations may be challenged to evolve in spatially heterogeneous environments, such as mixtures of host cells that pose differing selection pressures. Spatial heterogeneity may select for evolved polymorphisms, where multiple virus subpopulations coexist by specializing on a narrow subset of...

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Détails bibliographiques
Publié dans:Virus Evol
Auteurs principaux: Morley, Valerie J., Sistrom, Mark, Usme-Ciro, Jose A., Remold, Susanna K., Turner, Paul E.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989875/
https://ncbi.nlm.nih.gov/pubmed/27774292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vev022
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