The retina as an early biomarker of neurodegeneration in a rotenone-induced model of Parkinson’s disease: evidence for a neuroprotective effect of rosiglitazone in the eye and brain

Parkinson’s Disease (PD) is the second most common neurodegenerative disease worldwide, affecting 1 % of the population over 65 years of age. Dopaminergic cell death in the substantia nigra and accumulation of Lewy bodies are the defining neuropathological hallmarks of the disease. Neuronal death an...

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Enregistré dans:
Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Normando, Eduardo Maria, Davis, Benjamin Michael, De Groef, Lies, Nizari, Shereen, Turner, Lisa A., Ravindran, Nivedita, Pahlitzsch, Milena, Brenton, Jonathan, Malaguarnera, Giulia, Guo, Li, Somavarapu, Satyanarayana, Cordeiro, Maria Francesca
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989531/
https://ncbi.nlm.nih.gov/pubmed/27535749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0346-z
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