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Integrated analysis of DNA methylation, immunohistochemistry and mRNA expression, data identifies a Methylation Expression Index (MEI) robustly associated with survival of ER-positive breast cancer patients

Identification of prognostic gene expression signatures may enable improved decisions about management of breast cancer. To identify a prognostic signature for breast cancer, we performed DNA methylation profiling and identified methylation markers that were associated with expression of ER, PR, HER...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Figueroa, Jonine D., Yang, Howard, Garcia-Closas, Montserrat, Davis, Sean, Meltzer, Paul, Lissowska, Jolanta, Horne, Hisani N., Sherman, Mark E., Lee, Maxwell
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989123/
https://ncbi.nlm.nih.gov/pubmed/25773928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3314-6
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